Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8627816B2 · kind B2 · utility
42Cited by
291References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 28, 2011 |
| Grant date | Jan 14, 2014 |
| Priority date | — |
| Expiry date | Feb 4, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2210/0618
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.