Three-dimensional microfluidic devices

US8628729B2 · kind B2 · utility

Assignee

• President and Fellows of Harvard College · US

Inventors

• Emanuel Carrilho · Sharon, US
• Andres W. Martinez · Cambridge, US
• Katherine A. Mirica · Hanover, US
• Scott T. Phillips · Cambridge, US
• Adam Siegel · New York, US
• Benjamin Wiley · Durham, US
• George M. Whitesides · Newton, US

Key dates

• Filing date: Mar 27, 2009
• Grant date: Jan 14, 2014
• Expiry date: May 8, 2029

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/25
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

Three-dimensional microfluidic devices including by a plurality of patterned porous, hydrophilic layers and a fluid-impermeable layer disposed between every two adjacent patterned porous, hydrophilic layers are described. Each patterned porous, hydrophilic layer has a fluid-impermeable barrier which substantially permeates the thickness of the porous, hydrophilic layer and defines boundaries of one or more hydrophilic regions within the patterned porous, hydrophilic layer. The fluid-impermeable layer has openings which are aligned with at least part of the hydrophilic region within at least one adjacent patterned porous, hydrophilic layer. Microfluidic assay device, microfluidic mixer, microfluidic flow control device are also described.