Method of forming an implantable knitted fabric comprising silk fibroin fibers
US8628791B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 24, 2011 |
| Grant date | Jan 14, 2014 |
| Priority date | — |
| Expiry date | Mar 24, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T442/2566
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Silk is purified to eliminate immunogenic components (particularly sericin) and is used to form fabric that is used to form tissue-supporting prosthetic devices for implantation. The fabrics can carry functional groups, drugs, and other biological reagents. Applications include hernia repair, tissue wall reconstruction, and organ support, such as bladder slings. The silk fibers are arranged in parallel and, optionally, intertwined (e.g., twisted) to form a construct; sericin may be extracted at any point during the formation of the fabric, leaving a construct of silk fibroin fibers having excellent tensile strength and other mechanical properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.