Single cell nucleic acid analysis
US8628923B2 · kind B2 · utility
80Cited by
2References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 13, 2010 |
| Grant date | Jan 14, 2014 |
| Priority date | — |
| Expiry date | Aug 17, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/178
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods for analysis of genomic DNA and/or RNA from small samples or even single cells. Methods for analyzing genomic DNA can entail whole genome amplification (WGA), followed by preamplification and amplification of selected target nucleic acids. Methods for analyzing RNA can entail reverse transcription of the desired RNA, followed by preamplification and amplification of selected target nucleic acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.