Methods of inhibiting calcineurin with ApoE analogs
US8629242B2 · kind B2 · utility
1Cited by
4References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 31, 2008 |
| Grant date | Jan 14, 2014 |
| Priority date | — |
| Expiry date | May 22, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/775
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method of modulating calcineurin activity in a cell by contacting the cell with at least one ApoE analog. Methods of treating various disorders associated with calcineurin activity using one or more ApoE analogs are also disclosed. In particular, the present invention provides a method of reducing demyelination and promoting remyelination in a subject. Methods of treating spinal cord or nerve injury in a subject are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.