Method for producing phosphate-bridged nucleoside conjugates

US8629265B2 · kind B2 · utility

Assignee

• Universitaet Hamburg · DE

Inventors

• Chris Meier · Jork, DE
• Saskia Wolf · Hamburg, DE
• Svenja Warnecke · Mannheim, DE

Key dates

• Filing date: Aug 6, 2009
• Grant date: Jan 14, 2014
• Expiry date: Mar 11, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H19/173
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a method for producing phosphate-bridged nucleoside conjugates. In the method a nucleophile is first dissolved in a non-aqueous solvent and dried, and a cyclosaligenyl phosphate compound is subsequently added to the solution.