Patent · US Active

Method and apparatus for extended time and varying environment measurements of single particles in microfluidic channels

US8631685B2 · kind B2 · utility

3Cited by

0References

2Claims

0Family size

Assignee

Massachusetts Institute of Technology · US

Inventors

Scott Manalis · Cambridge, US
Andrea K. Bryan · Brookline, US
Michel Godin · Ottawa, CA
Philip Dextras · Cambridge, US
Sungmin Son · Cambridge, US
Thomas Burg · Cambridge, US
William H. Grover · Riverside, US
Yao-Chung Weng · Cambridge, US

Key dates

Filing date	Mar 23, 2010
Grant date	Jan 21, 2014
Priority date	—
Expiry date	Apr 5, 2032

Classification

Technology area (CPC G)Physics
CPC primaryG01N15/00
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Methods and apparatus for improving measurements of particle or cell characteristics, such as mass, in Suspended Microchannel Resonators (SMR's). Apparatus include in particular designs for trapping particles in SMR's for extended measurement periods and for changing the fluid properties within the SMR during the extended periods. Methods include techniques to provide for cell growth over time and over time in response to changing fluid properties to aid in determining parameters such as drug resistance and drug susceptibility.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.