Gene expression markers for prediction of patient response to chemotherapy
US8632980B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Oct 21, 2011 |
| Grant date | Jan 21, 2014 |
| Priority date | — |
| Expiry date | Oct 25, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In addition, the invention relates to a clinically validated cancer test, e.g. colorectal test, for assessment of prognosis and/or prediction of patient response to chemotherapy, using expression analysis. The present invention accommodates the use of archived paraffin embedded biopsy material for assay of all markers in the relevant gene sets and therefore is compatible with the most widely available type of biopsy material.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.