7-(1H-pyrazol-4-yl)-1,6-naphthyridine compounds as Syk inhibitors
US8633319B2 · kind B2 · utility
6Cited by
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11Claims
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Key dates
| Filing date | Apr 27, 2011 |
| Grant date | Jan 21, 2014 |
| Priority date | — |
| Expiry date | Apr 27, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a compound of formula (I):or a salt thereof;which is an inhibitor of spleen tyrosine kinase (Syk) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast and/or basophil cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory disease and/or allergic disorders, and in cancer therapy, specifically heme malignancies, chronic spontaneous urticaria and autoimmune conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.