Process for preparing bromo-substituted quinolines

US8633320B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Nitinchandra D. Patel · Danbury, US
• Chris Hugh Senanayake · Brookfield, US
• Wenjun Tang · Shanghai, CN
• Xudong Wei · West Greenwich, US
• Nathan K. Yee · Seattle, US

Key dates

• Filing date: May 3, 2010
• Grant date: Jan 21, 2014
• Expiry date: May 3, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F5/025
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed are methods for the preparation of bromo-substituted quinolines of the formula (I) where R is aryl, heteroaryl, alkyl, alkenyl or alkynyl, which are useful as intermediates in the preparation of agents for the treatment of hepatitis C viral (HCV) infections: Formula (I).