Recombinant vaccines and use thereof

US8637006B2 · kind B2 · utility

Assignee

• BioNTech AG · DE

Inventors

• Ozlem Tureci · Homburg, DE
• Ugur Sahin · Mainz, DE
• Sebastian Kreiter · Mainz, DE

Key dates

• Filing date: May 15, 2012
• Grant date: Jan 28, 2014
• Expiry date: May 15, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/03
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to fusion molecules of antigens, the nucleic acids coding therefor and the use of such fusion molecules and nucleic acids. In particular, said invention relates to fusion molecules, comprising an antigen and the trans-membrane region and cytoplasmic region of a MHC molecule and/or the cytoplasmic region of a MHC or a SNARE molecule.