Identification of a JAK2 mutation in polycythemia vera
US8637235B2 · kind B2 · utility
10Cited by
7References
3Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Sep 19, 2008 |
| Grant date | Jan 28, 2014 |
| Priority date | — |
| Expiry date | May 17, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative disorders, or to the detection of the JAK2 V617F variant in myeloproliferative disorders allowing their reclassification in a new nosological group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.