Methods of identifying modulators of olfactory receptors involved in the perception of sweat carboxylic acids
US8637259B1 · kind B1 · utility
2Cited by
0References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 9, 2011 |
| Grant date | Jan 28, 2014 |
| Priority date | — |
| Expiry date | Feb 9, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to the identification of carboxylic acids, present in human sweat, as natural ligands of a specific subgroup of seven olfactory receptor (OR) belonging to class 1 within the OR classification. The invention encompasses the use of the interaction of OR polypeptides and carboxylic acids as the basis of screening assays for agents that specifically modulate the activity of the seven ORs of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.