Compounds for the reduction of beta-amyloid production

US8637523B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Kenneth M. Boy · Durham, US
• Jason M. Guernon · Hamden, US
• John E. Macor · Guilford, US
• Lorin A. Thompson, III · Higganum, US
• Yong-Jin Wu · Madison, US
• Yunhui Zhang · Glastonbury, US

Key dates

• Filing date: Jul 12, 2011
• Grant date: Jan 28, 2014
• Expiry date: Jun 17, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula (I) are provided, including pharmaceutically acceptable salts thereof:which modulate β-amyloid peptide (β-AP) production, and are useful in the treatment of Alzheimer's Disease and other conditions affected by β-amyloid peptide (β-AP) production.