Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins
US8637578B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Jun 24, 2004 |
| Grant date | Jan 28, 2014 |
| Priority date | — |
| Expiry date | Jan 8, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H5/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Methods and reagents for the formation of disulfide bonds, particularly in proteins, peptides and amino acids. The methods and reagents are particularly useful for the controlled glycosylation of proteins, peptides and amino acids. The methods utilize thiosulfonate or selenenylsulfide compounds as reagents or intermediates. Some proteins and peptides comprising selenenyl-sulfide groups also form part of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.