Imidazo [4,5-C]quinoline derivatives and their use in the treatment of tumors and/or inflammation
US8637670B2 · kind B2 · utility
9Cited by
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13Claims
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Key dates
| Filing date | Jun 30, 2009 |
| Grant date | Jan 28, 2014 |
| Priority date | — |
| Expiry date | Jun 30, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides the compounds of formula (I):The present invention relates to imidazo[4,5-c]quinoline derivatives of formula (I), process for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases mediated by phosphatidylinositol-3-kinase (PBK) and/or mammalian target of rapamycin (mTOR) and/or tumor necrosis factor-α (TNF-oc) and/or interleukin-6 (IL-6), particularly in the treatment of cancer and inflammation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.