Patent · US Active

Methods and compositions for intraocular administration to treat ocular conditions

US8642067B2 · kind B2 · utility

4Cited by
62References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 2, 2007
Grant dateFeb 4, 2014
Priority date
Expiry dateNov 3, 2031

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K47/36
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Anti-angiogenesis compositions, and methods of using such compositions, useful for injection into the vitreous of human eyes are provided. Such compositions can include TKI component solutions or particles present in a therapeutically effective amount, a viscosity inducing component, and an aqueous carrier component. The compositions have viscosities at about 25° C. of at least about 10 cps or about 100 cps at a shear rate of 0.1/second. In a preferred embodiment, the viscosity at 25° C. is in the range of from about 80,000 cps to about 300,000 cps.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.