Materials and methods for hypothermic collection of whole blood
US8642255B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 27, 2009 |
| Grant date | Feb 4, 2014 |
| Priority date | — |
| Expiry date | Nov 17, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K35/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to materials and methods for hypothermic collection of whole blood, and components thereof, which can extend the holding time of blood beyond the current useable limit. Additionally, blood can be drawn directly into a hypothermic preservation solution without the addition of standard anticoagulants. This is enabled by providing sustained cellular viability under hypothermic conditions using a nutrient matrix devoid of animal proteins and containing energy substrates, free-radical scavengers, and impermeants that is ionically balanced for storage of biologic materials at low temperatures to prevent cellular stress-induced apoptosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.