Ligand sensing fluorescent acetylcholinesterase for detection of organophosphate activity
US8642273B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 16, 2003 |
| Grant date | Feb 4, 2014 |
| Priority date | — |
| Expiry date | Aug 7, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/18
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are methods for the preparation and use of labeled AChE and labeled AChE inhibitory conjugate compositions for detecting accumulation of toxic materials such as organophosphates, insecticides, and other nerve agents. Also disclosed are methods for the use of labeled AChE and labeled AChE inhibitory conjugate compositions in a variety of areas, including the detecting of toxic materials in biological samples, in the area of food and water analysis, in environmental monitoring, and in industrial settings.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.