Anterior ocular segment related cell sheets, three-dimensional structures, and processes for producing the same
US8642338B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 6, 2003 |
| Grant date | Feb 4, 2014 |
| Priority date | — |
| Expiry date | Oct 1, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K35/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An anterior ocular segment related cell sheet or three-dimensional structure that have only a few structural defects as they have been recovered retaining the intercellular desmosome structure and the basement membrane-like protein between cell and substrate. The anterior ocular segment related cell sheet or three-dimensional structure is produced by a process comprising the steps of cultivating cells on a cell culture support comprising a substrate having its surface covered with a temperature responsive polymer having an upper or lower critical dissolution temperature of 0-80° C. with respect to water, optionally stratifying the layer of cultured cells by the usual method, and thereafter,
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.