Compounds, compositions and methods for the treatment of poxvirus infections
US8642577B2 · kind B2 · utility
5Cited by
91References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 10, 2006 |
| Grant date | Feb 4, 2014 |
| Priority date | — |
| Expiry date | Jun 17, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/24034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application provides methods and compositions for combination therapy with antiviral compounds for the treatment of poxvirus infections, such as orthopox virus infections. In one embodiment, a method of treatment of a poxvirus infection is provided that comprises administering to a host in need thereof cidofovir, cyclic cidofovir, or a salt, ester, or prodrug thereof in combination or alternation with at least a second anti-poxvirus agent. The second anti-poxvirus agent is, for example, a biologic, such as a pegylated interferon.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.