Indanyloxydihydrobenzofuranylacetic acids

US8642585B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Matthias Eckhardt · Hannover, DE
• Sara Frattini · Castelleone, IT
• Dieter Hamprecht · Verona, IT
• Frank Himmelsbach · Mittelbiberach, DE
• Elke Langkopf · Biberach an der Riß, DE
• Iain Lingard · Monza, IT
• Stefan Peters · Biberach an der Riß, DE
• Holger Wagner · Mettenberg, DE

Key dates

• Filing date: Mar 14, 2013
• Grant date: Feb 4, 2014
• Expiry date: Mar 14, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of general formula I,wherein the groups R1, R2 and m are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.