Method for reducing the immune response to a biologically active protein
US8642743B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Apr 6, 2005 |
| Grant date | Feb 4, 2014 |
| Priority date | — |
| Expiry date | Jan 4, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/755
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new use of a molecule comprising at least one moiety which is a biologically active protein and at least one moiety capable of binding to a serum albumin of a mammal is provided, for preparation of a medicament which elicits no or a reduced immune response upon administration to the mammal, as compared to the immune response elicited upon administration to the mammal of the biologically active protein per se. Also provided is a method of reducing or eliminating the immune response elicited upon administration of a biologically active protein to a human or non-human mammal, which comprises coupling the polypeptide to at least one moiety capable of binding to a serum albumin of the mammal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.