Determining whether a test compound modulates PD-1 activity in activated immune cells using gene expression profiles
US8647822B2 · kind B2 · utility
2Cited by
1References
6Claims
0Family size
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Key dates
| Filing date | Nov 28, 2008 |
| Grant date | Feb 11, 2014 |
| Priority date | — |
| Expiry date | Feb 13, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/26
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Modulation of PD-1 activity in the presence or absence of an agent as measured by a gene expression profile of at least two genes is provided. Reagents, kits, methods and uses thereof for the modulation of immune function comprise the identification of modulators of PD-1 activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.