Artificial tissue constructs comprising alveolar cells and methods for using the same
US8647837B2 · kind B2 · utility
4Cited by
12References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 16, 2008 |
| Grant date | Feb 11, 2014 |
| Priority date | — |
| Expiry date | Nov 25, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention comprises artificial tissue constructs that serve as in vitro models of mammalian lung tissue. The artificial tissue constructs of the present invention comprise functionally equivalent in vitro tissue scaffolds that enable immunophysiological function of the lung. The constructs can serve as novel platforms for the study of lung diseases (e.g., interstitial lung diseases, fibrosis, influenza, RSV) as well as smoke- and smoking-related diseases. The artificial tissue constructs of the present invention comprise the two components of alveolar tissue, epithelial and endothelial cell layers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.