Patent · US Active

N4-phenyl-quinazoline-4-amine derivatives and related compounds as ErbB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases

US8648087B2 · kind B2 · utility

22Cited by

43References

37Claims

0Family size

Assignee

Array BioPharma, Inc. · US

Inventors

Joseph P. Lyssikatos · South San Francisco, US
Julie Marie Greschuk · Erie, US
Fredrik P. Marmsater · Longmont, US
Qian Zhao · Louisville, US
D. David Hennings · Boulder, US
Weidong Liu · Superior, US

Key dates

Filing date	Nov 15, 2006
Grant date	Feb 11, 2014
Priority date	—
Expiry date	Apr 9, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D519/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention provides compounds of Formula Iwherein B, G, A, E, R1, R2, R3, m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.