Diarylthiohydantoin compounds

US8648105B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Michael E. Jung · Los Angeles, US
• Dongwon Yoo · Los Angeles, US
• Charles L. Sawyers · New York, US
• Chris Tran · New York, US
• John Wongvipat · Nanuet, US

Key dates

• Filing date: Dec 21, 2011
• Grant date: Feb 11, 2014
• Expiry date: Dec 21, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D233/86
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to diarylthiohydantoin compounds and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.