Patent · US Active

Substituted piperazinyl-pyrrolidine compounds useful as chemokine receptor antagonists

US8648197B2 · kind B2 · utility

2Cited by
15References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 26, 2012
Grant dateFeb 11, 2014
Priority date
Expiry dateMar 26, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D473/32
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided:or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions for the inhibition of Chemokine Receptors and also for the treatment of various diseases, conditions, or disorders, including acute or chronic inflammatory disease, cancer or osteolytic bone disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.