Targeted perhydrolases

US8652455B2 · kind B2 · utility

Assignee

• E.I. DU PONT DE NEMOURS AND COMPANY · US

Inventors

• Robert DiCosimo · Chadds Ford, US
• Scott Cunningham · Chadds Ford, US
• Stephen R. Fahnestock · Wilmington, US
• Tanja Maria Gruber · Media, US
• Mark S. Payne · Wilmington, US
• Pierre E. Rouviere · Wilmington, US
• Linda Jane Solomon · Wilmington, US
• Hong Wang · Kennett Square, US

Key dates

• Filing date: Dec 19, 2011
• Grant date: Feb 18, 2014
• Expiry date: Dec 19, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/01
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Disclosed herein are compositions and methods to target enzymatic peracid production to a target surface. The peracid benefit agent produced by the targeted perhydrolytic enzyme can be use for a variety of applications such as bleaching, whitening, disinfecting, destaining, deodorizing, and combinations thereof. Specifically, a fusion protein comprising a perhydrolytic enzyme and at least one peptidic component having affinity for a target surface (excluding body surfaces and oral care surfaces) is used in combination with a suitable substrate and a source of peroxygen to enzymatically produce a peracid on or near the surface of the target material. In a preferred aspect, the target surface is a cellulosic material.