NSAID delivery from polyarylates
US8652525B2 · kind B2 · utility
8Cited by
18References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 8, 2009 |
| Grant date | Feb 18, 2014 |
| Priority date | — |
| Expiry date | May 3, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2017/00893
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides biodegradable, sustained-release pharmaceutical compositions of non-steroidal, anti-inflammatory drugs (NSAIDs) formulated with biocompatible, biodegradable tyrosine-derived polyarylates. The compositions are particularly suitable for localized delivery of NSAIDs for various disease states. For example, implantation of the compositions at the site of surgery leads to relatively high local concentrations of the NSAID to reduce or alleviate post-surgical pain. Long term zero order release of certain NSAIDs can also be provided by with certain polymer formulations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.