Dry composition of reaction compounds with stabilized polymerase

US8652811B2 · kind B2 · utility

Assignee

• Roche Diagnostics Operations, Inc. · US

Inventors

• Thomas Metzler · Munich, DE
• Tobias Haslinger · Penzberg, DE
• Annette Peceny · Wolfratshausen, DE
• Harald Sobek · Penzberg, DE

Key dates

• Filing date: Dec 18, 2009
• Grant date: Feb 18, 2014
• Expiry date: Jun 28, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/6876
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention provides methods to obtain dry compositions of reaction compounds that maintain the biological activity of the compounds upon re-solubilization after a certain storage time. Preferably, the dry composition comprises a polymerase, and the dry composition is usable for polymerase chain reaction (PCR) amplification after re-solubilization.