Pyrid-2yl fused heterocyclic compounds, and compositions and uses thereof

US8653091B2 · kind B2 · utility

Assignee

• EVOTEC AG · DE

Inventors

• Zhi-Liang Wei · South San Francisco, US
• John Kincaid · Hayward, US
• Michael G. Kelly · Thousand Oaks, US
• Donogh John Roger O'Mahony · San Mateo, US
• Carl Kaub · San Jose, US

Key dates

• Filing date: Mar 31, 2008
• Grant date: Feb 18, 2014
• Expiry date: Feb 21, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Fused heterocyclic compounds are provided according to formula 1a or 1b:where R1, R2, and R3 are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.