Substituted dihydropyrazolones for treating cardiovascular and hematological diseases

US8653111B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Kai Thede · Leverkusen, DE
• Ingo Flamme · Bergneustadt, DE
• Felix Oehme · Wuppertal, DE
• Jens-Kerim Ergüden · Uerdingen, DE
• Friederike Stoll · Mülheim an der Ruhr, DE
• Joachim Schuhmacher · Wuppertal, DE
• Hanno Wild · Wuppertal, DE
• Peter Kolkhof · Wuppertal, DE
• Hartmut Beck · Wuppertal, DE
• Jörg Keldenich · Wuppertal, DE
• Metin Akbaba · Ratingen, DE
• Mario Jeske · Solingen, DE

Key dates

• Filing date: Jan 23, 2012
• Grant date: Feb 18, 2014
• Expiry date: Jan 23, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.