Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
US8653118B2 · kind B2 · utility
1Cited by
5References
20Claims
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Key dates
| Filing date | Aug 19, 2011 |
| Grant date | Feb 18, 2014 |
| Priority date | — |
| Expiry date | Aug 19, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds, that are N-alkyl-2-(1-(5-substituted-2-(3-oxo-3-(trifluoromethylsulfon-amido)propyl)benzyl)pyrrolidin-2-yl)oxazole-4-carboxamide wherein the 5 substituent is selected from the group consisting of halo and alkyloxy radicals. The compound may be represented by the following formula wherein R1 is selected from the group consisting of CO2R7 and CON(R7)SO2R7 wherein R1, R2, R3, R4, and R7 are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, EP3, TP and/or EP4 receptor mediated diseases or conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.