Crystalline ingenol mebutate
US8653133B2 · kind B2 · utility
2Cited by
0References
27Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 18, 2011 |
| Grant date | Feb 18, 2014 |
| Priority date | — |
| Expiry date | Oct 26, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a novel crystalline form of ingenol mebutate, methods of preparation thereof, and to its use. More specifically, the invention relates to the conversion of amorphous ingenol mebutate (ingenol-3-angelate, PEP005) to a crystalline form, which was characterized by single crystal X-Ray crystallography (XRC), attenuated total reflectance Fourier transform infrared (FTIR-ATR) spectroscopy and Differential Scanning calorimetry (DSC).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.