Dibenzothiazepine derivatives and uses thereof—424

US8653257B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Dean Brown · Wilmington, US
• James R. Damewood · Wilmington, US
• Phil Edwards · Wilmington, US
• James Hulsizer · Wilmington, US
• James Campbell Muir · Macclesfield, GB
• M. Edward Pierson, Jr. · Wilmington, US
• Ashokkumar B. Shenvi · Wilmington, US
• Steven Wesolowski · Natick, US
• Dan Widzowski · Wilmington, US
• Michael R. Wood · Harleysville, US

Key dates

• Filing date: Apr 12, 2012
• Grant date: Feb 18, 2014
• Expiry date: May 21, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D281/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds the following formula:wherein Z is as described in the specification, pharmaceutically acceptable salts thereof, compositions comprising the same, and methods of treating bipolar disorder, an anxiety disorder, a mood disorder or schizophrenia or other psychotic disorder with said compounds.