5,6-bisaryl-2-pyridine-carboxamide derivatives, preparation thereof and therapeutic application thereof as urotensin II receptor antagonists
US8653276B2 · kind B2 · utility
3Cited by
0References
11Claims
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Assignee
Inventors
Key dates
| Filing date | May 15, 2013 |
| Grant date | Feb 18, 2014 |
| Priority date | — |
| Expiry date | May 15, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds of the general formula:as defined herein, and pharmaceutical compositions thereof. The invention is also directed to their therapeutic use as urotensin II receptor antagonists, e.g., in the treatment of cardiac, coronary, and central nervous system disorders. In particular embodiments, the invention relates to 5,6-bisaryl-2-pyridinecarboxamides, to their preparation and to their therapeutic use as urotensin II receptor antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.