Patent · US Active

Isoform selective HDAC inhibitors

US8653278B2 · kind B2 · utility

5Cited by
0References
10Claims
0Family size

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Inventors

Key dates

Filing dateAug 2, 2007
Grant dateFeb 18, 2014
Priority date
Expiry dateOct 19, 2027

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

One aspect of the invention relates to isoform-selective HDAC inhibitors. Also provided are methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy. The invention also provides methods for treating cancer, methods for treating neurological diseases and methods for treating malaria. Additionally, the invention provides pharmaceutical compositions comprising an HDAC inhibitor of the invention; and kits comprising an HDAC inhibitor of the invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.