Polyurethane plaster for the transdermal application of active substances, and method for the production thereof

US8657986B2 · kind B2 · utility

Assignee

• Otto Bock PUR LifeScience GmbH · DE

Inventors

• Peter Gansen · Selters (Westerwald), DE
• Michael Dittgen · Apolda, DE
• Ingeborg Steinfatt-Hoffmann · Freiburg im Breisgau, DE
• Christian Schulte · Eppelheim, DE
• Juergen Henze · Duderstadt, DE

Key dates

• Filing date: Nov 26, 2009
• Grant date: Feb 25, 2014
• Expiry date: May 22, 2030

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/1476
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for producing an active substance-containing polyurethane plaster for transdermal application is described, said plaster containing at least one active substance at a highly accurate declared dose. In the described method, a solvent-free active substance-containing polyurethane is produced by reactively coating a solvent-free active substance-containing polyurethane material (40), which is mixed in a coating unit (60) immediately before or during the application process, onto an elastic backing foil (20) that has been rendered non-extensible at least in the direction in which the applied polyurethane material is processed by means of a supporting, adhering auxiliary foil (30) which is at least mono-axially non-extensible.