Patent · US Active

Binding of aggregated forms of proteins

US8658374B2 · kind B2 · utility

0Cited by

6References

32Claims

0Family size

Assignee

Microsens Biphage Limited · GB

Inventors

Amin Reza Lane · Leatherhead, GB
Christopher J. Stanley · London, GB
Stuart Wilson · Sutton, GB

Key dates

Filing date	Jul 14, 2011
Grant date	Feb 25, 2014
Priority date	—
Expiry date	Jul 14, 2031

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/2828
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Aggregating proteins such as IgG, are bound selectively in the presence of the non-aggregated protein using a polyionic binding agent such as dextran sulphate or pentosan (anionic), or polyamine compounds such as pDADMAC (cationic) under selective binding conditions including the use of n-lauroylsarcosine at mildly alkaline pH, and may then be assayed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.