Substituted oxazole derivatives and their use as tyrosine kinase inhibitors
US8658659B2 · kind B2 · utility
1Cited by
28References
13Claims
0Family size
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Key dates
| Filing date | Jan 5, 2012 |
| Grant date | Feb 25, 2014 |
| Priority date | — |
| Expiry date | Jan 5, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel compounds selected from substituted oxazole derivatives of formula (I) that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective c-kit, bcr-abl and Flt-3 inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.