Treatment of hyperproliferative disorders with diarylhydantoin compounds

US8658681B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Charles L. Sawyers · New York, US
• Michael E. Jung · Los Angeles, US
• Charlie D. Chen · Los Angeles, US
• Samedy Ouk · San Diego, US
• Chris Tran · New York, US
• John Wongvipat · Nanuet, US

Key dates

• Filing date: Apr 17, 2012
• Grant date: Feb 25, 2014
• Expiry date: Apr 17, 2032

Classification

• Technology area (CPC —): General

Abstract

The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.