Synthesis of 2′,3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization
US8658776B2 · kind B2 · utility
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Key dates
| Filing date | May 26, 2011 |
| Grant date | Feb 25, 2014 |
| Priority date | — |
| Expiry date | Dec 27, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6806
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Methods for preparation of 2′,3′-dideoxynucleotides support structures, such as 2′,3′-dideoxyguanosine, 2′,3′-dideoxyadenosine, and 3′-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.