Patent · US Active

Stereoselective synthesis of bicyclic heterocycles

US8658790B2 · kind B2 · utility

1Cited by

1References

3Claims

0Family size

Assignee

Boehringer Ingelheim International GmbH · DE

Inventors

Markus Ostermeier · Biberach an der Riß, DE
Juergen Daeubler · Biberach an der Riß, DE
Guenther Huchler · Biberach an der Riß, DE
Stephan Kling · Warthausen, DE
Marco Santagostino · Magenta, IT

Key dates

Filing date	Jul 30, 2010
Grant date	Feb 25, 2014
Priority date	—
Expiry date	Aug 25, 2031

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a process for the stereoselective preparation of compounds of formulae (1A) and (1B)and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids and bases, which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, the use thereof for the treatment of diseases, particularly tumoral diseases as well as benign prostatic hyperplasia (BPH), diseases of the lungs and airways.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.