Method for diagnosing and monitoring cardiac ischemia in patients with acute chest pain and without myocardial infarction
US8663941B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 24, 2012 |
| Grant date | Mar 4, 2014 |
| Priority date | — |
| Expiry date | May 24, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/324
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present disclosure relates to a method for diagnosing the ischemic state in a subject suffering from acute coronary syndrome who does not fulfilling the diagnostic criteria for a myocardial infarction. The present disclosure also relates to a method for identifying a subject being susceptible to cardiac intervention, wherein the subject suffers from acute coronary syndrome but does not fulfill the diagnostic criteria for a myocardial infarction. The methods of the present disclosure are based on the determination of fms-like tyrosine kinase-1 (sFLT-1) and, optionally, hepatocyte growth factor (HGF) in a sample of said subject. The present disclosure also relates to kits and/or devices for carrying out the methods disclosed herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.