Patent · US Active

Mesenchymal stem cells for the treatment of CNS diseases

US8663987B2 · kind B2 · utility

7Cited by

9References

6Claims

0Family size

Assignees

Ramot at Tel-Aviv University Ltd. · IL
BRAINSTORM CELL THERAPEUTICS LTD. · IL

Inventors

Avinoam Kadouri · Netanya, IL
Avihay Bar-Ilan · Nes Ziona, IL
Eldad Melamed · Nes Ziona, IL
Daniel Offen · Gdera, IL
Ofer Sadan · Nes Ziona, IL
Merav Bahat-Stromza · Haifa, IL

Key dates

Filing date	May 26, 2009
Grant date	Mar 4, 2014
Priority date	—
Expiry date	Feb 11, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2506/1353
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.