Substituted amino-quinazolinones, medicaments comprising said compound, their use and their method of manufacture

US8664388B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Klaus Fuchs · Ingelheim am Rhein, DE
• Niklas Heine · Eberhardzell, DE
• Christian Eickmeier · Mittelbiberach, DE
• Sandra Handschuh · Biberach an der Riß, DE
• Cornelia Dorner-Ciossek · Ingelheim am Rhein, DE
• Stefan Hoerer · Biberach an der Riß, DE

Key dates

• Filing date: Jun 14, 2012
• Grant date: Mar 4, 2014
• Expiry date: Jun 14, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to substituted amino-quinazolinones of general formula (I) wherein the groups R1 to R14 and A, are defined as in the specification and claims and the use thereof for the treatment of Alzheimer's disease (AD) and similar diseases.