Purification 4-aza-androst-1-ene-17-oic acid from 4-aza-androstan-17-oic acid
US8664395B2 · kind B2 · utility
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Key dates
| Filing date | Apr 2, 2009 |
| Grant date | Mar 4, 2014 |
| Priority date | — |
| Expiry date | Jan 8, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J73/005
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process of separation of 4-aza-androst-1-ene-17-oic acid from 4-aza-androstan-17-oic acid, which brings to 4-aza-androst-1-ene-17-oic containing less than 0.05% w/w of 4-aza-androstan-17-oic acid, with high yield and productivity. In particular, the present invention relates to a process for the separation of 4-aza-androstan-17-oic acid from 4-aza-androst-1-ene-17-oic acid, comprising the steps of treating the crude 4-aza-androst-1-ene-17-oic acid with formic acid and recovering the purified 4-aza-androst-1-ene-17-oic acid containing 4-aza-androstan-17-oic acid in w/w % less than 0.05%.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.