Implantable biomedical devices on bioresorbable substrates

US8666471B2 · kind B2 · utility

Assignees

• The Board of Trustees of the University of Illinois · US
• Northwestern University · US
• Trustees of Tufts College · US
• The Trustees of the University of Pennsylvania · US

Inventors

• John A. Rogers · Champaign, US
• Dae-Hyeong Kim · Champaign, US
• Fiorenzo G. Omenetto · Wakefield, US
• David L. Kaplan · Seattle, US
• Brian Litt · Yeadon, US
• Jonathan Viventi · Durham, US
• Yonggang Huang · Glencoe, US
• Jason Amsden · Eddington, US

Key dates

• Filing date: Sep 28, 2010
• Grant date: Mar 4, 2014
• Expiry date: Jun 18, 2031

Classification

• Technology area (CPC H): Electricity
• CPC primary: H05K3/20
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Provided herein are implantable biomedical devices, methods of administering implantable biomedical devices, methods of making implantable biomedical devices, and methods of using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment. Each implantable biomedical device comprises a bioresorbable substrate, an electronic device having a plurality of inorganic semiconductor components supported by the bioresorbable substrate, and a barrier layer encapsulating at least a portion of the inorganic semiconductor components. Upon contact with a biological environment the bioresorbable substrate is at least partially resorbed, thereby establishing conformal contact between the implantable biomedical device and the target tissue in the biological environment.