Method for determining the likelihood that a test polynucleotide sequence differs from a driver polynucleotide
US8666669B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 29, 2001 |
| Grant date | Mar 4, 2014 |
| Priority date | — |
| Expiry date | Mar 30, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B30/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates generally is a method for determining the likelihood that a test polynucleotide sequence differs from a driver polynucleotide sequence. More particularly, the present method uses fluorescence-based technology in the assessment of the results of competitive hybridization between polynucleotide sequences. The present method does not require nucleotide sequencing or gel electrophoresis and is capable of being multiplexed and automated. The methods of the present invention will find broad application in the analysis of polynucleotides, inter alia in genetic analysis, specific locus testing, genotyping, mutation detection, the discovery and detection of single nucleotide polymorphisms (SNPs) and mapping.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.